Product Overview
Blocking/Immunizing peptide for anti-JUNB antibody
Tag/Conjugate
Unconjugated
Application Notes
For in vitro research use only. Not intended for any diagnostic or therapeutic purpose. Not for human or animal consumption.
Format
Lyophilized powder
Storage
Shipped at ambient temperature, store at -20°C.
Antigen Description
JUNB (jun B proto-oncogene) is a protein-coding gene. Diseases associated with JUNB include cascade stomach, and anaplastic large cell lymphoma, and among its related super-pathways are Mucin expression in CF via IL-6, IL-17 signaling pathways and G-protein signaling Ras family GTPases in kinase cascades (scheme). GO annotations related to this gene include transcription corepressor activity and sequence-specific DNA binding transcription factor activity. An important paralog of this gene is JUND.
Function
DNA binding; double-stranded DNA binding; protein binding; protein dimerization activity; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; transcription coactivator activity; transcription corepressor activity;
Synonyms
JUNB; jun B proto-oncogene; transcription factor jun-B; activator protein 1; AP-1;
Citations
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Ronca, F; Chan, SL; et al. 1-(5-isoquinolinesulfonyl)-2-methylpiperazine induces apoptosis in human neuroblastoma cells, SH-SY5Y, through a p53-dependent pathway. JOURNAL OF BIOLOGICAL CHEMISTRY 272:4252-4260(1997).
Mao, X; Orchard, G; et al. Abnormal activator protein 1 transcription factor expression in CD30-positive cutaneous large-cell lymphomas. BRITISH JOURNAL OF DERMATOLOGY 157:914-921(2007).