Human JMJD4 peptide

Nature

Synthetic

Tag/Conjugate

Unconjugated

SequenceSimilarities

17 amino acids near the amino terminus of human JMJD4.

Purity

> 95 % by SDS-PAGE.

Format

Lyophilized

Preservative

None

Storage

Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. Information available upon request.

Reconstitution

JMJD4 peptide is supplied as 1mg of dried peptide. When the peptide is reconstituted in 1 mL strile water, the concentration will be 1 mg/mL.

Introduction

JMJD4 has been reported to hydroxylate specific lysine residues on target proteins involved in the translation machinery, thereby influencing translational termination efficiency. Through this post-translational modification, JMJD4 contributes to the regulation of protein synthesis and cellular homeostasis. Its enzymatic activity depends on cofactors such as Fe(II) and 2-oxoglutarate, which are characteristic of JmjC domain-containing dioxygenases.

Entrez Gene ID

Synonyms

JMJD4; jumonji domain containing 4; jmjC domain-containing protein 4; jumonji domain-containing protein 4;