Synthetic Human JARID2 blocking peptide for Apuri, BL, ELISA
Blocking/Immunizing peptide for anti-JARID2 antibody
Human, Mouse, Cow, Dog, Pig, Rat
For in vitro research use only. Not intended for any diagnostic or therapeutic purpose. Not for human or animal consumption.
Shipped at ambient temperature, store at -20°C.
This gene encodes a Jumonji- and AT-rich interaction domain (ARID)-domain-containing protein. The encoded protein is a DNA-binding protein that functions as a transcriptional repressor. This protein interacts with the Polycomb repressive complex 2 (PRC2) which plays an essential role in regulating gene expression during embryonic development. This protein facilitates the recruitment of the PRC2 complex to target genes. Alternate splicing results in multiple transcript variants. Mutations in this gene are associated with chronic myeloid malignancies. [provided by RefSeq, May 2012]
DNA binding; chromatin binding; NOT histone demethylase activity;
JARID2; jumonji, AT rich interactive domain 2; JMJ, jumonji (mouse) homolog , Jumonji, AT rich interactive domain 2; protein Jumonji; jumonji homolog; jumonji-like protein; jumonji/ARID domain-containing protein 2; JMJ;