General Notes
This product (Catalog No. CABT-BL1943) is a rabbit-derived IgG polyclonal antibody raised against human IQCJ, targeting the amino acid region 31–130 of the protein. This antibody exhibits cross-reactivity with IQCJ from mouse, rat, dog, pig, horse, rabbit, and sheep. It has been affinity purified by protein A. IQ motif containing J (IQCJ) is a protein characterized by the presence of an IQ motif, a conserved calmodulin-binding sequence that typically mediates calcium-independent interactions with calmodulin. IQCJ is predominantly expressed in the nervous system and has been implicated in neuronal development and function, particularly in processes related to axon growth and signal transduction. Although its molecular mechanisms are not yet fully defined, the presence of the IQ motif suggests a role in calcium-related signaling pathways that regulate cytoskeletal dynamics and neuronal connectivity. IQCJ is therefore considered a putative regulator of calmodulin-dependent processes in neural cells, warranting further functional investigation.
CABT-BL1943 is suitable for use in IHC-P (1:100–1:500), IHC-F (1:100–1:500), IF (immunofluorescence) (1:100–1:500) applications.
CABT-BL1943 is supplied as a liquid formulation in 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. For long-term storage, keep at −20 °C. For short-term use, store at 2–8 °C. Avoid repeated freeze–thaw cycles to maintain antibody integrity and performance.
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