Native Humanproteinase 3 (PR3). Isolated from human peripheral blood leukocytes.
SDS-PAGE;capillary electrophoresis (purity > 80% in the sum of differentglycosylation isoforms according to following section); Western blot withrabbit anti-PR3 antisera and mouse anti-PR3 monoclonal antibodies.
0.5-1.0μg/ml (depending on the type of ELISA plate and coating buffer). Suitable forbiotinylation and iodination.
Ionicstrength around 400 mM, neutral to slightly acidic pH, low concentration of aneutral detergent.
2-8°C short term, -20°C long term
Proteinase 3 also known as PRTN3 is an enzyme that in humans is encoded by the PRTN3 gene.
Proteinase 3 alsoknown as PRTN3 is an enzyme which in humans is encoded by the PRTN3 gene.
PRTN3; proteinase 3; myeloblastin; ACPA; AGP7; C ANCA; MBT; P29; PR 3; serine proteinase; neutrophil; Wegener granulomatosis autoantigen; NP-4; C-ANCA antigen; wegener autoantigen; leukocyte proteinase 3; neutrophil proteinase 4; azurophil granule protein