Product Overview
Recombinant human HBXIP protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
Alternative Names
Hepatitis B virus x interacting protein; XIP; HBXIP; Human HBXIP
Purity
> 90%, based on SDS PAGE
Concentration
Batch dependent - please inquire should you have specific requirements.
Buffer
In 20mM Tris-HCl buffer (pH 8.0) containing 0.1M NaCl, 10% glycerol,1mM EDTA
Storage
Can be stored at 4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
Introduction
Hepatitis B virus x interacting protein, also known as HBXIP, was originally identified by its ability to form a complex with the C-terminus of hepatitis B virus X (HBX) protein. HBXIP negatively regulates the activity of HBX and alters the replicative life cycle of the virus. In addition, HBXIP is involved in bipolar spindle formation and regulates centrosome dynamics and cytokinesis in cells, possibly through an interaction with Dynein light chain.
Keywords
Hepatitis B virus x interacting protein;XIP;HBXIP;Human HBXIP
Citations
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