Genome-wide association study of meat quality traits in chicken
GENETICS AND MOLECULAR RESEARCH
Authors: Zhang, T.; Fan, Q. C.; Wang, J. Y.; Zhang, G. X.; Gu, Y. P.; Tang, Y.
Abstract
Meat quality traits are very important in the poultry industry. To identify single nucleotide polymorphisms (SNPs) and candidate genes affecting meat quality traits, a genome-wide association study was performed using the Illumina chicken 60K SNP beadchip in Jinghai yellow chicken. Four meat quality traits were measured. Two SNPs reached 5% Bonferroni genome-wide significance (P < 1.8E-6) and 7 SNPs reached "suggestive" genomewide significance (P < 3.59E-6) with meat quality. These SNPs were located nearby or in 7 candidate genes, including CBLN2, HPGDS, SETD2, and ANKRD46, among others. A total of 5650 haplotpyes were established and only 1 was found to be associated with fat content in leg muscle. These results indicate that the 9 SNPs and 7 genes are important candidate markers and may influence meat quality traits in chicken.
Loss of Expression of SWI/SNF Chromatin Remodeling Complex Components and SetD2 Are Heterogeneous, Widespread, and Co-Occur in Clear Cell Renal Cell Carcinoma
LABORATORY INVESTIGATION
Authors: Jiang, Wei; Dulaimi, Essel; Parsons, Theodore; Wang, Qiong; Devarajan, Karthik; O'Neill, Raymond; Solomides, Charalambos; Peiper, Stephen; Testa, Joseph; Uzzo, Robert; Yang, Haifeng
Abstract
COA
Publication 
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