Human HVCN1 blocking peptide (CDBP1529)

Synthetic Human HVCN1 blocking peptide for BL

Product Overview
Blocking peptide for anti-HVCN1 antibody
Target
HVCN1
Nature
Synthetic
Species Reactivity
Human
Tag/Conjugate
Unconjugated
Application Notes
For in vitro research use only. Not intended for any diagnostic or therapeutic purpose. Not suitable for human or animal consumption.
Procedure
None
Format
Liquid
Concentration
200 μg/ml
Size
50 μg
Buffer
PBS containing 0.02% sodium azide
Preservative
0.02% Sodium Azide
Storage
Store at -20℃, stable for one year.
UniProt ID
Antigen Description
This gene encodes a voltage-gated protein channel protein expressed more highly in certain cells of the immune system. Phagocytic cells produce superoxide anions which require this channel protein, and in B cells this same process facilitates antibody production. This same channel protein, however, can also regulate functions in other cells including spermatozoa. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012]
Function
voltage-gated ion channel activity; voltage-gated proton channel activity; voltage-gated proton channel activity;
Synonyms
HVCN1; hydrogen voltage-gated channel 1; voltage-gated hydrogen channel 1; Hv1; MGC15619; voltage sensor domain only protein; VSOP; voltage sensor domain-only protein; HV1;

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References


Sasaki, M; Tojo, A; et al. Autoimmune disorder phenotypes in Hvcn1-deficient mice. BIOCHEMICAL JOURNAL 450:295-301(2013).
Demaurex, N; El Chemaly, A; et al. Physiological roles of voltage-gated proton channels in leukocytes. JOURNAL OF PHYSIOLOGY-LONDON 588:4659-4665(2010).

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