HRH4 peptide

Specificity

Expressed primarily in the bone marrow and eosinophils. Shows preferential distribution in cells of immunological relevance such as T-cells, dendritic cells, monocytes, mast cells, neutrophils. Also expressed in a wide variety of peripheral tissues, inclu

Nature

Synthetic

Tag/Conjugate

Unconjugated

SequenceSimilarities

Belongs to the G-protein coupled receptor 1 family.

Purity

70 - 90% by HPLC.

Preservative

None

Storage

Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. Information available upon request.

Entrez Gene ID

Antigen Description

Histamine is a ubiquitous messenger molecule released from mast cells, enterochromaffin-like cells, and neurons. Its various actions are mediated by a family of histamine receptors, which are a subset of the G-protein coupled receptor superfamily. This gene encodes a histamine receptor that is predominantly expressed in haematopoietic cells. The protein is thought to play a role in inflammation and allergy reponses. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2009]

Function

histamine receptor activity;

Synonyms

HRH4; histamine receptor H4; H4; H4R; BG26; HH4R; AXOR35; GPRv53; GPCR105; histamine H4 receptor; SP9144; pfi-013; G-protein coupled receptor 105;