Product Overview
Blocking/Immunizing peptide for anti-HOXD13 antibody
Tag/Conjugate
Unconjugated
Application Notes
For in vitro research use only. Not intended for any diagnostic or therapeutic purpose. Not for human or animal consumption.
Format
Lyophilized powder
Storage
Shipped at ambient temperature, store at -20°C.
Antigen Description
This gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, located on different chromosomes, consisting of 9 to 11 genes arranged in tandem. This gene is one of several homeobox HOXD genes located in a cluster on chromosome 2. Deletions that remove the entire HOXD gene cluster or the 5' end of this cluster have been associated with severe limb and genital abnormalities. Mutations in this particular gene cause synpolydactyly. [provided by RefSeq, Jul 2008]
Function
DNA binding; chromatin binding; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity;
Synonyms
HOXD13; homeobox D13; BDE; SPD; BDSD; HOX4I; homeobox protein Hox-D13; homeo box 4I; homeo box D13; homeobox protein Hox-4I;
Citations
Publication ()
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