In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. This gene is part of the A cluster on chromosome 7 and encodes a DNA-binding transcription factor which may regulate gene expression, morphogenesis, and differentiation. [provided by RefSeq, Jul 2008]
Function
sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity;
Synonyms
HOXA6; homeobox A6; HOX1; HOX1B; HOX1.2; homeobox protein Hox-A6; homeo box 1B; homeo box A6; homeobox protein HOXA6; homeobox protein Hox-1B;
Citations
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