Anti-HMX2 monoclonal antibody (DMABT-H13963)

Mouse anti-Human HMX2 monoclonal antibody for WB, IHC, IF, ELISA Datasheet

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Specifications


Host Species
Mouse
Antibody Isotype
IgG2b
Clone
2E8
Species Reactivity
Human
Immunogen
HMX2 (NP_005510, 125 a.a. ~ 224 a.a) full length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Conjugate
Unconjugated

Target


Alternative Names
HMX2; H6 family homeobox 2; homeo box (H6 family) 2; homeobox protein HMX2; NKX5 2; H6 homeo box 2
Entrez Gene ID
UniProt ID

Product Background


Gene summary
HMX2 (H6 Family Homeobox 2) is a Protein Coding gene. Diseases associated with HMX2 include cecal benign neoplasm and cecum adenocarcinoma. GO annotations related to this gene include sequence-specific DNA binding. An important paralog of this gene is DLX5. The protein encoded by this gene is a member of the NKL homeobox family of transcription factors. Members in this family are of ancient origin and play an important role in organ development during embryogenesis. A related mouse protein plays a role in patterning of inner ear structures. In humans, variations in a region containing this gene have been associated with inner ear malformations, vestibular dysfunction, and hearing loss.
Antigen Description
Transcription factor involved in specification of neuronal cell types and which is required for inner ear and hypothalamus development. The function about HMX2 antigen include sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity.

Citations


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References


Ito, S; Ichinose, H; et al. Identification of differentially expressed genes in susceptible and resistant responses of Chinese cabbage to Plasmodiophora brassicae. JOURNAL OF PHYTOPATHOLOGY-PHYTOPATHOLOGISCHE ZEITSCHRIFT 149:227-231(2001).
Martinez, P; Davidson, EH; et al. SpHmx, a sea urchin homeobox gene expressed in embryonic pigment cells. DEVELOPMENTAL BIOLOGY 181:213-222(1997).

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