Anti-HMX2 monoclonal antibody (DMABT-H13963)
Mouse anti-Human HMX2 monoclonal antibody for WB, IHC, IF, ELISA
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HMX2 (NP_005510, 125 a.a. ~ 224 a.a) full length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
HMX2; H6 family homeobox 2; homeo box (H6 family) 2; homeobox protein HMX2; NKX5 2; H6 homeo box 2
HMX2 (H6 Family Homeobox 2) is a Protein Coding gene. Diseases associated with HMX2 include cecal benign neoplasm and cecum adenocarcinoma. GO annotations related to this gene include sequence-specific DNA binding. An important paralog of this gene is DLX5. The protein encoded by this gene is a member of the NKL homeobox family of transcription factors. Members in this family are of ancient origin and play an important role in organ development during embryogenesis. A related mouse protein plays a role in patterning of inner ear structures. In humans, variations in a region containing this gene have been associated with inner ear malformations, vestibular dysfunction, and hearing loss.
Transcription factor involved in specification of neuronal cell types and which is required for inner ear and hypothalamus development. The function about HMX2 antigen include sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity.
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Munroe, RJ; Prabhu, V; et al. Mouse H6 Homeobox 1 (Hmx 1) mutations cause cranial abnormalities and reduced body mass. BMC DEVELOPMENTAL BIOLOGY 9:-(2009).
Jones, CT; Morrice, DR; et al. Gene homologs on human Chromosome 15q21-q26 and a chicken microchromosome identify a new conserved segment. MAMMALIAN GENOME 8:436-440(1997).
Custom Antibody Labeling
We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody.