Product Overview
NS3 (HCV) (NP_671491, 1225 a.a.-1456 a.a.) partial recombinant protein with His tag expressed in Escherichia coli .
Purity
Conventional Chromatography
Buffer
In 20 mM Tris-HCl, pH 8.0 (10% glycerol, 1 mM DTT)
Storage
2-8°C short term, -20°C long term
Introduction
The hepatitis C virus (HCV) core protein represents the first 191 amino acids of the viral precursor polyprotein and is cotranslationally inserted into the membrane of the endoplasmic reticulum. Hepatitis C virus (HCV) core is a viral structural protein; it also participates in some cellular processes, including transcriptional regulation. However the mechanisms of core-mediated transcriptional regulation remain poorly understood. Hepatitis C virus (HCV) core protein is thought to contribute to HCV pathogenesis through its interaction with various signal transduction pathways. In addition, HCV core antigen is a recently developed marker of hepatitis C infection. The HCV core protein has been previously shown to circulate in the bloodstream of HCV-infected patients and inhibit host immunity through an interaction with gC1qR.
Keywords
HCV NS3 transactivated protein; NS 3; NS3; NS3P; p70; Serine protease/NTPase/helicase; Hepatitis C Virus NS3; Flaviviridae; Hepacivirus; Hepatitis C virus; HCV NS-3; HCV NS3 Genotype 1a; Hepatitis C Virus NS3 Genotype 1a
Citations
Publication ()
Have you cited DAG1700 in a publication?
Let us know and earn a reward for your research.
COA
Loading ......
