General Notes
This product (Catalog No. CABT-BL1706) is a rabbit-derived IgG polyclonal antibody raised against human GTF3C6, targeting the amino acid region 51–150 of the protein. This antibody exhibits cross-reactivity with GTF3C6 from mouse, rat, dog, pig, cow, horse, rabbit, and sheep. It has been affinity purified by protein A. RNA polymerases are unable to initiate RNA synthesis in the absence of additional proteins called general transcription factors (GTFs). GTFs assemble in a complex on the DNA promoter and recruit the RNA polymerase. GTF3C family proteins (e.g., GTF3C1, MIM 603246) are essential for RNA polymerase III to make a number of small nuclear and cytoplasmic RNAs, including 5S RNA (MIM 180420), tRNA, and adenovirus-associated (VA) RNA of both cellular and viral origin.
CABT-BL1706 is suitable for use in IHC-P (1:100–1:500), IHC-F (1:100–1:500), IF (immunofluorescence) (1:100–1:500), ICC/IF (1:100–1:500), ELISA (1:5,000–1:10,000) applications.
CABT-BL1706 is supplied as a liquid formulation in 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. For long-term storage, keep at −20 °C. For short-term use, store at 2–8 °C. Avoid repeated freeze–thaw cycles to maintain antibody integrity and performance.
Alternative Names
bA397G5.3; C6ORF51; General transcription factor 3C polypeptide 6; General transcription factor IIIC polypeptide 6 alpha; GTF3C6; TF3C6_HUMAN; TFIIIC 35 kDa subunit; TFIIIC35; Transcription factor IIIC 35 kDa subunit; Transcription factor IIIC 35kDa; Transcription factor IIIC polypeptide 6; Transcription factor IIIC subunit 6
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