Human GNRHR blocking peptide (CDBP1429)

Synthetic Human GNRHR blocking peptide for Apuri, BL, ELISA Datasheet

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Product Overview
Blocking/Immunizing peptide for anti-GRHR/LRHR antibody
Target
GRHR / LRHR
Nature
Synthetic
Species Reactivity
Human, Dog
Tag/Conjugate
Unconjugated
Application Notes
For in vitro research use only. Not intended for any diagnostic or therapeutic purpose. Not for human or animal consumption.
Format
Lyophilized powder
Size
100 μg
Storage
Shipped at ambient temperature, store at -20°C.
UniProt ID
Antigen Description
This gene encodes the receptor for type 1 gonadotropin-releasing hormone. This receptor is a member of the seven-transmembrane, G-protein coupled receptor (GPCR) family. It is expressed on the surface of pituitary gonadotrope cells as well as lymphocytes, breast, ovary, and prostate. Following binding of gonadotropin-releasing hormone, the receptor associates with G-proteins that activate a phosphatidylinositol-calcium second messenger system. Activation of the receptor ultimately causes the release of gonadotropic luteinizing hormone (LH) and follicle stimulating hormone (FSH). Defects in this gene are a cause of hypogonadotropic hypogonadism (HH). Alternative splicing results in multiple transcript variants encoding different isoforms. More than 18 transcription initiation sites in the 5' region and multiple polyA signals in the 3' region have been identified for this gene.
Function
gonadotropin-releasing hormone receptor activity; growth hormone-releasing hormone receptor activity; receptor activity; signal transducer activity;
Synonyms
GNRHR; gonadotropin-releasing hormone receptor; GRHR; LHRHR; gnRH-R; gnRH receptor; luliberin receptor; type I GnRH receptor; leutinizing-releasing hormone receptor; leutinizing hormone releasing horomone receptor; gonadotropin-releasing hormone (type 1) receptor 1; LRHR; GNRHR1;

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