Human GPI blocking peptide (CDBP1402)

Synthetic Human GPI blocking peptide for Apuri, BL, ELISA Datasheet

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Product Overview
Blocking/Immunizing peptide for anti-GPI/Neuroleukin antibody
GPI / Neuroleukin
Species Reactivity
Human, Pig
Application Notes
For in vitro research use only. Not intended for any diagnostic or therapeutic purpose. Not for human or animal consumption.
Lyophilized powder
100 μg
Shipped at ambient temperature, store at -20°C.
UniProt ID
Antigen Description
This gene encodes a member of the glucose phosphate isomerase protein family. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. In the cytoplasm, the gene product functions as a glycolytic enzyme (glucose-6-phosphate isomerase) that interconverts glucose-6-phophsate and fructose-6-phosphate. Extracellularly, the encoded protein (also referred to as neuroleukin) functions as a neurotrophic factor that promotes survival of skeletal motor neurons and sensory neurons, and as a lymphokine that induces immunoglobulin secretion. The encoded protein is also referred to as autocrine motility factor based on an additional function as a tumor-secreted cytokine and angiogenic factor. Defects in this gene are the cause of nonspherocytic hemolytic anemia and a severe enzyme deficiency can be associated with hydrops fetalis, immediate neonatal death and neurological impairment. Alternative splicing results in multiple transcript variants.
cytokine activity; glucose-6-phosphate isomerase activity; glucose-6-phosphate isomerase activity; growth factor activity; isomerase activity;
GPI; glucose-6-phosphate isomerase; glucose phosphate isomerase; AMF; NLK; neuroleukin; oxoisomerase; sperm antigen 36; sperm antigen-36; phosphohexomutase; phosphosaccharomutase; phosphohexose isomerase; phosphoglucose isomerase; autocrine motility factor; hexosephosphate isomerase; hexose monophosphate isomerase; PGI; PHI; GNPI; SA36; SA-36; DKFZp686C13233;


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