Cardiac Magnetic Resonance Myocardial Feature Tracking for Optimized Risk Assessment After Acute Myocardial Infarction in Patients With Type 2 Diabetes
DIABETES
Authors: Backhaus, Soeren J.; Kowallick, Johannes T.; Stiermaier, Thomas; Lange, Torben; Navarra, Jenny-Lou; Koschalka, Alexander; Evertz, Ruben; Lotz, Joachim; Kutty, Shelby; Hasenfuss, Gerd; Gutberlet, Matthias; Thiele, Holger; Eitel, Ingo; Schuster, Andreas
Abstract
Type 2 diabetes predicts outcome following acute myocardial infarction (AMI). Since underlying mechanics are incompletely understood, we investigated left ventricular (LV) and left atrial (LA) pathophysiological changes and their prognostic implications using cardiovascular magnetic resonance (CMR). Consecutive patients (N= 1,147;n= 265 with diabetes,n= 882 without diabetes) underwent CMR 3 days after AMI. Analyses included LV ejection fraction (LVEF); global longitudinal strain (GLS) and circumferential and radial strains; LA reservoir, conduit, and booster pump strains; and infarct size, edema, and microvascular obstruction. Predefined end points were major adverse cardiovascular events (MACE) within 12 months. Patients with diabetes had impaired LA reservoir (19.8% vs. 21.2%,P< 0.01) and conduit (7.6% vs. 9.0%,P< 0.01) strains but not ventricular function or myocardial damage. They were at higher risk of MACE than patients without diabetes (10.2% vs. 5.8%,P< 0.01), with most MACE occurring in patients with LVEF >= 35%. While LVEF (P= 0.045) and atrial reservoir strain (P= 0.024) were independent predictors of MACE in patients without diabetes, GLS was in patients with diabetes (P= 0.010). Considering patients with diabetes and LVEF >= 35% (n= 237), GLS and LA reservoir strain below median were significantly associated with MACE. In conclusion, in patients with diabetes, LA and LV longitudinal strain permit optimized risk assessment early after reperfused AMI with incremental prognostic value over and above that of LVEF.
On the relationship between sport and financial performances: an empirical investigation
MANAGERIAL FINANCE
Authors: Di Simone, Luca; Zanardi, Davide
Abstract
Purpose Our paper shows an empirical analysis of the European football companies to test the association between sport results, proxied by ranking position and financial performance in panel framework (starting from 59 firms over the 2013-2018 time span). Design/methodology/approach We use panel data models for studying the relationship of our interest and we make no a priori assumption about the strict exogeneity of the covariates and estimate equation using both Random Effects GLS (RE-GLS) and Fixed Effects OLS (FE-OLS) estimations. Findings Our results suggest there is stable and significant relationship between the two types of performance and that when detectable this is linked in a positive way to the profit maximization of the business model, suggesting that it is more useful for investor remuneration and to increase technical-tactical resources and therefore sports results. Not surprisingly, as for many clubs, concentration effect is relevant while the financial fair play regulation is not. In fact, the current regulation of UEFA authority does not seem to have an impact on sport and financial results. Originality/value This work complements literature in several ways. First, we offer new empirical evidence for the association between the sport and financial performance for a panel of the European football companies, listed and not. Second, we show that the persistence of the sport results is strongly correlated with financial performance.