Product Overview
Blocking/Immunizing peptide for anti-GADD45gamma (aa 123 to 133) antibody
Target
GADD45gamma (aa 123 to 133)
Tag/Conjugate
Unconjugated
Application Notes
For in vitro research use only. Not intended for any diagnostic or therapeutic purpose. Not for human or animal consumption.
Format
Lyophilized powder
Storage
Shipped at ambient temperature, store at -20°C.
Antigen Description
This gene is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. The protein encoded by this gene responds to environmental stresses by mediating activation of the p38/JNK pathway via MTK1/MEKK4 kinase. The GADD45G is highly expressed in placenta. [provided by RefSeq, Jul 2008]
Function
protein binding;
Synonyms
GADD45G; growth arrest and DNA-damage-inducible, gamma; CR6; DDIT2; GRP17; GADD45gamma; growth arrest and DNA damage-inducible protein GADD45 gamma; DDIT-2; GADD45-gamma; gadd-related protein, 17 kD; cytokine-responsive protein CR6; DNA damage-inducible transcript 2 protein;
Citations
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Sasaki, Y; Ohtani, T; et al. Molecular Events in Human T Cells Treated with Diesel Exhaust Particles or Formaldehyde that Underlie Their Diminished Interferon-gamma and Interleukin-10 Production. INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY 148:239-250(2009).
Xu, JH; Qiu, W; et al. Gene expression profile and overexpression of apoptosis-related genes (NGFI-B and Gadd 45 gamma) in early phase of Thy-1 nephritis model. CELL AND TISSUE RESEARCH 326:159-168(2006).
COA
Certificate of Analysis
