Sample
milk, serum, meat, shrimp, egg, urine, feed, honey, water
Species Reactivity
Bovine, Sheep, Poultry, Rabbit, Goat, Horse, Salmonidae
Intended Use
Flumequine is a second generation quinolone antibiotic and is mainly active against Gram negative bacteria. It is used in bovine, ovine, poultry, rabbits, goats, horses and salmonidae. As all other (fluoro)quinolones, flumequine acts by inhibiting bacterial DNA-gyrase, thus disrupting its activity by interfering with the DNA annealing reaction. The MRLs for flumequine in the different matrices depend on the matrix and the species from which the matrix originates.
Detection Limit
13 ppb for milk, 1 ppb for serum, <0.1 ppb for meat, <0.1 ppb for shrimp, 3.5 ppb for egg, 5.5 ppb for urine, 10 ppb for feed, <10 ppb for honey, 3 ppb for water
Citations
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Zhu, Y; Li, L; et al. Development of an immunochromatography strip for the rapid detection of 12 fluoroquinolones in chicken muscle and liver. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY 56:5469-5474(2008).
Pinacho, DG; Sanchez-Baeza, F; et al. Molecular Modeling Assisted Hapten Design To Produce Broad Selectivity Antibodies for Fluoroquinolone Antibiotics. ANALYTICAL CHEMISTRY 84:4527-4534(2012).