Human FBLN5 blocking peptide

Product Overview

Blocking/Immunizing peptide for anti-Fibulin 5/FBLN5 antibody

Target

Fibulin 5 / FBLN5

Nature

Synthetic

Tag/Conjugate

Unconjugated

Application Notes

For in vitro research use only. Not intended for any diagnostic or therapeutic purpose. Not for human or animal consumption.

Format

Lyophilized powder

Preservative

None

Storage

Shipped at ambient temperature, store at -20°C.

Entrez Gene ID

Antigen Description

The protein encoded by this gene is a secreted, extracellular matrix protein containing an Arg-Gly-Asp (RGD) motif and calcium-binding EGF-like domains. It promotes adhesion of endothelial cells through interaction of integrins and the RGD motif. It is prominently expressed in developing arteries but less so in adult vessels. However, its expression is reinduced in balloon-injured vessels and atherosclerotic lesions, notably in intimal vascular smooth muscle cells and endothelial cells. Therefore, the protein encoded by this gene may play a role in vascular development and remodeling. Defects in this gene are a cause of autosomal dominant cutis laxa, autosomal recessive cutis laxa type I (CL type I), and age-related macular degeneration type 3 (ARMD3). [provided by RefSeq, Jul 2008]

Function

calcium ion binding; integrin binding; protein C-terminus binding; protein binding;

Synonyms

FBLN5; fibulin 5; EVEC; UP50; ADCL2; ARMD3; DANCE; ARCL1A; FIBL-5; fibulin-5; urine p50 protein; developmental arteries and neural crest EGF-like protein;