This gene encodes a member of the major facilitator superfamily of transporter proteins. The encoded protein is a heme transporter that may play a critical role in erythropoiesis by protecting developing erythroid cells from heme toxicity. This gene may play a role in posterior column ataxia with retinitis pigmentosa and the hematological disorder Diamond-Blackfan syndrome. [provided by RefSeq, Jan 2011]
Function
heme transporter activity; heme transporter activity; protein binding; transporter activity;
Synonyms
FLVCR1; feline leukemia virus subgroup C cellular receptor 1; PCA; AXPC1; FLVCR; PCARP; MFSD7B; feline leukemia virus subgroup C receptor-related protein 1;
Citations
Publication ()
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