Human ALOX5AP blocking peptide

Product Overview

Blocking/Immunizing peptide for anti-FLAP/ALOX5AP (internal) antibody

Target

FLAP / ALOX5AP (internal)

Nature

Synthetic

Tag/Conjugate

Unconjugated

Application Notes

For in vitro research use only. Not intended for any diagnostic or therapeutic purpose. Not for human or animal consumption.

Format

Lyophilized powder

Preservative

None

Storage

Shipped at ambient temperature, store at -20°C.

Entrez Gene ID

Antigen Description

This gene encodes a protein which, with 5-lipoxygenase, is required for leukotriene synthesis. Leukotrienes are arachidonic acid metabolites which have been implicated in various types of inflammatory responses, including asthma, arthritis and psoriasis. This protein localizes to the plasma membrane. Inhibitors of its function impede translocation of 5-lipoxygenase from the cytoplasm to the cell membrane and inhibit 5-lipoxygenase activation. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Feb 2011]

Function

arachidonic acid binding; enzyme activator activity; enzyme binding; NOT glutathione peroxidase activity; NOT glutathione transferase activity; NOT leukotriene-C4 synthase activity; protein N-terminus binding; protein binding; protein heterodimerization a

Synonyms

ALOX5AP; arachidonate 5-lipoxygenase-activating protein; FLAP; MK-886-binding protein;