The FYVE domain mediates the recruitment of proteins involved in membrane trafficking and cell signaling to phosphatidylinositol 3-phosphate (PtdIns(3)P)-containing membranes. This gene encodes a protein which contains a single FYVE domain and multiple WD40 repeats. This protein is localized to endosomes. [provided by RefSeq, Jul 2008]
Function
1-phosphatidylinositol binding; zinc ion binding;
Synonyms
WDFY1; WD repeat and FYVE domain containing 1; WDF1; FENS-1; ZFYVE17; WD repeat and FYVE domain-containing protein 1; WD40 and FYVE domain containing 1; phosphoinositide-binding protein 1; phosphoinositide-binding protein SR1; WD40- and FYVE domain-containing protein 1; zinc finger FYVE domain-containing protein 17;
Citations
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