Rabbit Anti-Human FAM76B (a.a. 179-277) Polyclonal antibody

Antibody Isotype

IgG

Species Reactivity

Human; Mouse

Immunogen

Recombinant human FAM76B protein; Source: E. coli derived, PGEX-4T; Tag: GST; Domain: 179-277 aa of NM_144664.4

Conjugate

Application Notes

WB: 1:1000-1:8000

General Notes

This product (Catalog No. CABT-BL1483) is a rabbit-derived polyclonal antibody raised against human FAM76B, targeting the amino acid region 179–277 of the protein. This antibody exhibits cross-reactivity with Human FAM76B from mouse. It has been affinity purified by Protein A. FAM76B is a nuclear protein with a molecular weight of about 39 kDa. Its amino acid sequence is highly conserved, and it is highly similar to FAM76B sequence of rats, mice and zebrafish. The protein contains histidine repeat sequence (poly-His domain) and ubiquitination site of Lys-225. FAM76B inhibits the inflammatory reaction mediated by NF-κB by affecting the cytoplasmic translocation of hnRNPA2B1. The expression of inflammatory factors (such as IL-6) increased significantly in FAM76B gene knockout mice, indicating that FAM76B has anti-inflammatory effect.
CABT-BL1483 is suitable for use in Western blot (WB) (1:1,000–1:8,000) application.
CABT-BL1483 is supplied as a liquid formulation in PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. For long-term storage, keep at −20 °C. For short-term use, store at 2–8 °C. Avoid repeated freeze–thaw cycles to maintain antibody integrity and performance.

Alternative Names

Protein FAM76B; FAM76B

Entrez Gene ID

UniProt ID