Human ESRRA peptide

Nature

Synthetic

Tag/Conjugate

Unconjugated

SequenceSimilarities

Belongs to the nuclear hormone receptor family. NR3 subfamily.Contains 1 nuclear receptor DNA-binding domain.

Purity

> 90 % by SDS-PAGE.This peptide is greater than 70% pure.

Format

Liquid

Buffer

Double distilled water or equivalent after reconstitution.

Preservative

None

Storage

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. Double distilled water or equivalent after reconstitution.

Entrez Gene ID

Antigen Description

The protein encoded by this gene is a nuclear receptor that is closely related to the estrogen receptor. This protein acts as a site-specific transcription regulator and has been also shown to interact with estrogen and the transcripton factor TFIIB by direct protein-protein contact. The binding and regulatory activities of this protein have been demonstrated in the regulation of a variety of genes including lactoferrin, osteopontin, medium-chain acyl coenzyme A dehydrogenase (MCAD) and thyroid hormone receptor genes. A processed pseudogene of ESRRA is located on chromosome 13q12.1. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Sep 2013]

Function

DNA binding; ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity; protein binding; protein domain specific binding; sequence-specific DNA binding; steroid binding; steroid hormone receptor activity; zinc ion bind

Synonyms

ESRRA; estrogen-related receptor alpha; ERR1; ERRa; ESRL1; NR3B1; ERRalpha; steroid hormone receptor ERR1; ERR-alpha; estrogen receptor-like 1; estrogen-related nuclear receptor alpha; nuclear receptor subfamily 3 group B member 1;