Eddp [KLH]

Name: Eddp [KLH]
SKU: DAGA-260K
Rating: 5 (1 reviews)

Eddp KLH Conjugated, Synthetic antigen for Immunogen

COA

SDS

Datasheet

Summary

Nature

Synthetic

Tag/Conjugate

KLH

Alternative Names

BAY 78418; bay78418; BAYER 78418; bayer78418; Blastoff; Dithiophosphorsaeure-O-aethyl-S; S-diphenylester; Ediphenophos; Ediphenphos; Lutrol; O-Aethyl-S; S-diphenyl-dithiophosphat; Phosphorodithioic acid; O-ethyl S; S-diphenyl ester; phosphorodithioicacid; o-ethyl-s; s-diphenylester; SRA 7847; sra7847; VIHINO; O-ETHYL S; S-DIPHENYL PHOSPHORODITHIOATE; HINORABCIDE; HINOSAN; HINOSAN(R); EDDP; EDIFEN; EDIFENFOS; EDIFENPHOS; EDISAN; edinphensoph; EDIFENPHOS PESTANAL (O-ETHYL S; S-DIPHENY); EDIFENPHOS; 500MG; NEAT; eddp (jmaf); edifenphos (bsi; iso); ENDINFENPHOS; O-ETHYLDIPHENYLPHOSPHORODITHIOLATE; EDINFENPHOS; edifenphos (ISO) O-ethyl S; S-diphenyl phosphorodithioate; Edifenphos E.C.; (Ethoxy-phenylsulfanylphosphoryl) sulfanylbenzene; S; S-Diphenyl O-ethyl phosphorodithioate; Dithiophosphoric acid O-ethyl S; S-diphenyl ester; Dithiophosphoric acid=O-ethyl=S; S-diphenyl ester; Phosphorodithioic acid O-ethyl S; S-diphenyl; EDIPHENFOS; Edifenphos 100mg [17109-49-8]; EDIFENPHOS; 100MG; NEAT

Format

Liquid

Concentration

Batch dependent - please inquire should you have specific requirements.

Buffer

0.01M pH7.4 PBS

Preservative

None

Storage

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

Keywords

Citations

Have you cited DAGA-260K in a publication? Let us know and earn a reward for your research.

Documents

pdf COA

pdf SDS

pdf Datasheet

QA & Reviews

Customer Reviews

References

Electrospray mass spectrometric studies of a potential antitumor drug and its analogous platinum(II) and platinum(IV) complexes with the ethylenediamine-N,N '-di-3-propanoato ligand and its dibutyl ester

MONATSHEFTE FUR CHEMIE

Authors: Kaluderovic, Goran N.; Vasiljevic, Tanja M.; Lausevic, Mila D.; Gaballa, Akmal S.; Sabo, Tibor J.

Abstract

The electrospray mass spectrometric (ESI-MS) behavior of the complexes trans-dichloro(ethylenediamine-N, N'-di-3-propionato) platinum(IV), trans-dibromo(ethylenediamine-N, N'-di-3-propionato) platinum( IV), dichloro (ethylenediamine-N,N'-di-3-propionic acid) platinum(II), tetrachloro(O,O'-di-n-butyl-ethylenediamine-N,N'-di-3-propanoate) platinum(IV), chlorotribromo(O,O'-di-n-butylethylenediamine-N,N'-di-3-propanoate) platinum(IV), and dichloro(O,O'-di-n-butyl-ethylenediamine-N,N'-di-3-propanoate) platinum( II), with the formulae trans-[PtCl2 (eddp)] (1), trans-[PtBr2(eddp)] (2), [PtCl2(H(2)eddp)] (3), [PtCl4(Bu(2)eddp)] (4), [PtBr3Cl(Bu(2)eddp)] (5), and [PtCl2(Bu(2)eddp)]center dot H2O (6), is reported. The deprotonated molecular ions or halide adducts are usually observed. ESI-MS data demonstrate the usefulness of the method for efficient characterization of metal complexes in solution.

Methadone metabolism by early gestational age placentas

AMERICAN JOURNAL OF PERINATOLOGY

Authors: Hieronymus, Todd Lewis; Nanovskaya, Tatiana N.; Deshmukh, Sujal V.; Vargas, Ricardo; Hankins, Gary D. V.; Ahmed, Mahmoud S.

Abstract

The objective of this study was to identify the enzyme that metabolizes methadone in preterm placentas. Microsomal fractions were obtained from preterm (17 to 34 weeks) placentas (36 total; 12 per each gestational age group) and their activity in metabolizing methadone to 2-ethylidene-1,5-dimethyl-3,3-diphenylpyrrolidine (EDDP) was determined. The enzyme catalyzing the reaction was identified by using chemical inhibitors selective for various cytochrome P450 isozymes and monoclonal antibodies raised against them. The metabolism of methadone by microsomes revealed saturation kinetics. Methadone was N-demethylated to EDDP by aromatase. The affinity of methadone to aromatase (apparent K-m) did not change with gestation, but the activity of the enzyme (V-max) increased and varied widely between individual placentas. Aromatase/CY-P19 is the placental enzyme metabolizing methadone during pregnancy. The variability in enzyme activity among individuals should be reflected by the concentration of methadone in the fetal circulation and might be one of the factors affecting the incidence and intensity of neonatal abstinence syndrome.