Anti-ERN1 monoclonal antibody (DMABT-H13690)

Mouse anti-Human ERN1 monoclonal antibody for WB, IHC, sELISA, ELISA Datasheet

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Specifications


Host Species
Mouse
Antibody Isotype
IgG1
Clone
4E2
Species Reactivity
Human
Immunogen
ERN1 (AAC25991,502a.a. ~ 500 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Conjugate
Unconjugated

Target


Alternative Names
ERN1; endoplasmic reticulum to nucleus signaling 1; ER to nucleus signalling 1; serine/threonine-protein kinase/endoribonuclease IRE1; inositol requiring enzyme 1; IRE1
Entrez Gene ID
UniProt ID

Product Background


Pathway
Activation of Chaperones by IRE1alpha, organism-specific biosystem; Alzheimers disease, organism-specific biosystem; Alzheimers disease, conserved biosystem; Diabetes pathways, organism-specific biosystem; Disease, organism-specific biosystem; Protein processing in endoplasmic reticulum, organism-specific biosystem; Protein processing in endoplasmic reticulum, conserved biosystem;

Citations


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References


Sasaki-Osugi, K; Imoto, C; et al. Nuclear ALG-2 Protein Interacts with Ca2+ Homeostasis Endoplasmic Reticulum Protein (CHERP) Ca2+-dependently and Participates in Regulation of Alternative Splicing of Inositol Trisphosphate Receptor Type 1 (IP(3)R1) Pre-mRNA. JOURNAL OF BIOLOGICAL CHEMISTRY 288:33361-33375(2013).
Mao, W; Fukuoka, S; et al. Cardiomyocyte apoptosis in autoimmune cardiomyopathy: mediated via endoplasmic reticulum stress and exaggerated by norepinephrine. AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY 293:H1636-H1645(2007).

Custom Antibody Labeling


We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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