This gene encodes a transcriptional regulator that belongs to the EGR family of C2H2-type zinc-finger proteins. It is an immediate-early growth response gene which is induced by mitogenic stimulation. The protein encoded by this gene participates in the transcriptional regulation of genes in controling biological rhythm. It may also play a role in a wide variety of processes including muscle development, lymphocyte development, endothelial cell growth and migration, and neuronal development. Alternative splicing results in multiple transcript variants encoding distinct isoforms.[provided by RefSeq, Dec 2010]
Function
DNA binding; metal ion binding; sequence-specific DNA binding transcription factor activity;
Synonyms
EGR3; early growth response 3; EGR-3; PILOT; early growth response protein 3; zinc finger protein pilot;
Citations
Publication ()
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