Product Overview
Blocking/Immunizing peptide for anti-EBAG9/RCAS1 antibody
Tag/Conjugate
Unconjugated
Application Notes
For in vitro research use only. Not intended for any diagnostic or therapeutic purpose. Not for human or animal consumption.
Format
Lyophilized powder
Storage
Shipped at ambient temperature, store at -20°C.
Antigen Description
This gene was identified as an estrogen-responsive gene. Regulation of transcription by estrogen is mediated by estrogen receptor, which binds to the estrogen-responsive element found in the 5'-flanking region of this gene. The encoded protein is a tumor-associated antigen that is expressed at high frequency in a variety of cancers. Alternate splicing results in multiple transcript variants. A pseudogene of this gene has been defined on chromosome 10.
Function
apoptotic protease activator activity;
Synonyms
EBAG9; estrogen receptor binding site associated, antigen, 9; receptor-binding cancer antigen expressed on SiSo cells; EB9; RCAS1; cancer associated surface antigen; cancer-associated surface antigen RCAS1; estrogen receptor-binding fragment-associated gene 9 protein; PDAF;
Citations
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Wicherek, L; Dutsch, M; et al. Comparative analysis of RCAS1 level in neoplasms and placenta. ACTA BIOCHIMICA POLONICA 50:1187-1194(2003).
Fujimura, T; Takahashi, S; et al. Estrogen receptor-binding fragment-associated gene 9 expression and its clinical significance in human testicular cancer. INTERNATIONAL JOURNAL OF UROLOGY 16:329-332(2009).