Rabbit Anti-Human E4F1 Polyclonal antibody

Antibody Isotype

IgG

Species Reactivity

Human; Mouse

Immunogen

A synthesized peptide derived from human E4F1.

Conjugate

Application Notes

ELISA 1:20000-1:40000

General Notes

This product (Catalog No. CABT-BL1336) is a rabbit-derived polyclonal antibody raised against human E4F1. This antibody exhibits cross-reactivity with E4F1 from mouse. It has been affinity purified by Protein A. May function as a transcriptional repressor. May also function as a ubiquitin ligase mediating ubiquitination of chromatin-associated TP53. Functions in cell survival and proliferation through control of the cell cycle. Functions in the p53 and pRB tumor suppressor pathways and regulates the cyclin CCNA2 transcription. Identified as a cellular target of the adenoviral oncoprotein E1A, it is required for both transcriptional activation and repression of viral genes.
CABT-BL1336 is suitable for use in ELISA 1 (20000-1:40000) application.
CABT-BL1336 is supplied as a liquid formulation in Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. For long-term storage, keep at −20 °C. For short-term use, store at 2–8 °C. Avoid repeated freeze–thaw cycles to maintain antibody integrity and performance.

Entrez Gene ID

UniProt ID