Synthetic Human DUOX1 blocking peptide for Apuri, BL, ELISA
Blocking/Immunizing peptide for anti-Dual oxidase 1 antibody
For in vitro research use only. Not intended for any diagnostic or therapeutic purpose. Not for human or animal consumption.
Shipped at ambient temperature, store at -20°C.
The protein encoded by this gene is a glycoprotein and a member of the NADPH oxidase family. The synthesis of thyroid hormone is catalyzed by a protein complex located at the apical membrane of thyroid follicular cells. This complex contains an iodide transporter, thyroperoxidase, and a peroxide generating system that includes proteins encoded by this gene and the similar DUOX2 gene. This protein is known as dual oxidase because it has both a peroxidase homology domain and a gp91phox domain. This protein generates hydrogen peroxide and thereby plays a role in the activity of thyroid peroxidase, lactoperoxidase, and in lactoperoxidase-mediated antimicrobial defense at mucosal surfaces. Two alternatively spliced transcript variants encoding the same protein have been described for this gene.
NAD(P)H oxidase activity; NADP binding; calcium ion binding; electron carrier activity; flavin adenine dinucleotide binding; heme binding; oxidoreductase activity; peroxidase activity;
DUOX1; dual oxidase 1; flavoprotein NADPH oxidase; LNOX1; NADPH thyroid oxidase 1; nicotinamide adenine dinucleotide phosphate oxidase; NOXEF1; THOX1; long NOX 1; large NOX 1; thyroid oxidase 1; MGC138840; MGC138841;