Product Overview
Blocking/Immunizing peptide for anti-DTX1/Deltex-1 antibody
Tag/Conjugate
Unconjugated
Application Notes
For in vitro research use only. Not intended for any diagnostic or therapeutic purpose. Not for human or animal consumption.
Format
Lyophilized powder
Storage
Shipped at ambient temperature, store at -20°C.
Antigen Description
Studies in Drosophila have identified this gene as encoding a positive regulator of the Notch-signaling pathway. The human gene encodes a protein of unknown function; however, it may play a role in basic helix-loop-helix transcription factor activity. [provided by RefSeq, Jul 2008]
Function
Notch binding; SH3 domain binding; ligase activity; protein binding; transcription coactivator activity; ubiquitin protein ligase binding; zinc ion binding;
Synonyms
DTX1; deltex 1, E3 ubiquitin ligase; hDx-1; E3 ubiquitin-protein ligase DTX1; hDTX1; deltex1; deltex homolog 1; protein deltex-1;
Citations
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TAKAI, A; MURATA, M; et al. INHIBITORY EFFECT OF OKADAIC ACID-DERIVATIVES ON PROTEIN PHOSPHATASES - A STUDY ON STRUCTURE AFFINITY RELATIONSHIP. BIOCHEMICAL JOURNAL 284:539-544(1992).
Gupta-Rossi, N; Storck, S; et al. Specific over-expression of deltex and a new Kelch-like protein in human germinal center B cells. MOLECULAR IMMUNOLOGY 39:791-799(2003).