Studies in Drosophila have identified this gene as encoding a positive regulator of the Notch-signaling pathway. The human gene encodes a protein of unknown function; however, it may play a role in basic helix-loop-helix transcription factor activity. [provided by RefSeq, Jul 2008]
Function
Notch binding; SH3 domain binding; ligase activity; protein binding; transcription coactivator activity; ubiquitin protein ligase binding; zinc ion binding;
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