Synthetic Human DPM1 blocking peptide for Apuri, BL, ELISA
Blocking/Immunizing peptide for anti-DPM1 antibody
For in vitro research use only. Not intended for any diagnostic or therapeutic purpose. Not for human or animal consumption.
Shipped at ambient temperature, store at -20°C.
Dolichol-phosphate mannose (Dol-P-Man) serves as a donor of mannosyl residues on the lumenal side of the endoplasmic reticulum (ER). Lack of Dol-P-Man results in defective surface expression of GPI-anchored proteins. Dol-P-Man is synthesized from GDP-mannose and dolichol-phosphate on the cytosolic side of the ER by the enzyme dolichyl-phosphate mannosyltransferase. Human DPM1 lacks a carboxy-terminal transmembrane domain and signal sequence and is regulated by DPM2.
alcohol binding; dolichyl-phosphate beta-D-mannosyltransferase activity; dolichyl-phosphate-mannose-protein mannosyltransferase activity; mannose binding; protein binding; transferase activity, transferring glycosyl groups;
DPM1; dolichyl-phosphate mannosyltransferase polypeptide 1, catalytic subunit; dolichol-phosphate mannosyltransferase; CDGIE; MPDS; DPM synthase; MPD synthase; mannose-P-dolichol synthase; dolichol-phosphate mannose synthase; dolichol monophosphate mannose synthase; dolichyl-phosphate beta-D-mannosyltransferase;