General Notes
This product (Catalog No. CABT-BL1312) is a rabbit-derived IgG polyclonal antibody raised against human DOLK, targeting the amino acid region 401–500 of the protein. This antibody exhibits cross-reactivity with DOLK from mouse, rat, chicken, pig, cow, horse, and sheep. It has been affinity purified by Protein A. The protein encoded by this gene catalyzes the CTP-mediated phosphorylation of dolichol, and is involved in the synthesis of Dol-P-Man, which is an essential glycosyl carrier lipid for C- and O-mannosylation, N- and O-linked glycosylation of proteins, and for the biosynthesis of glycosyl phosphatidylinositol anchors in endoplasmic reticulum. Mutations in this gene are associated with dolichol kinase deficiency.
CABT-BL1312 is suitable for use in Western blot (WB) (1:500–1:2,000) application.
CABT-BL1312 is supplied as a liquid formulation in 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. For long-term storage, keep at −20 °C. For short-term use, store at 2–8 °C. Avoid repeated freeze–thaw cycles to maintain antibody integrity and performance.
Alternative Names
CDG1M; DK; DK1; Dolichol kinase; KIAA1094; DOLK_HUMAN; SEC59; SEC59, YEAST, HOMOLOG OF; TMEM15; Transmembrane protein 15