Specificity
Highly expressed in heart, present at lower levels in liver, ileum, jejunum, colon, and kidney.
Tag/Conjugate
Unconjugated
SequenceSimilarities
Belongs to the cytochrome P450 family.
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. Information available upon request.
Antigen Description
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and is thought to be the predominant enzyme responsible for epoxidation of endogenous arachidonic acid in cardiac tissue. [provided by RefSeq, Jul 2008]
Function
arachidonic acid 11,12-epoxygenase activity; arachidonic acid 14,15-epoxygenase activity; arachidonic acid epoxygenase activity; aromatase activity; heme binding; iron ion binding; linoleic acid epoxygenase activity;
Synonyms
CYP2J2; cytochrome P450, family 2, subfamily J, polypeptide 2; CPJ2; cytochrome P450 2J2; CYPIIJ2; microsomal monooxygenase; arachidonic acid epoxygenase; flavoprotein-linked monooxygenase; cytochrome P450, subfamily IIJ (arachidonic acid epoxygenase) polypeptide 2;
Citations
Publication ()
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COA
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