General Notes
This product (Catalog No. CABT-BL4452) is a rabbit-derived polyclonal antibody raised against human CTRB1, targeting the amino acid region 34–261 of the protein. This antibody exhibits cross-reactivity with Human CTRB1 from mouse and rat. It has been affinity purified by Protein A. CTRB1 (chymotrypsinogen B1) encodes a pancreatic digestive enzyme precursor that belongs to the serine protease family. CTRB1 is synthesized and secreted by pancreatic acinar cells as the inactive zymogen chymotrypsinogen B1, which is subsequently activated in the small intestine to form chymotrypsin B, an enzyme responsible for hydrolyzing peptide bonds after aromatic amino acid residues during protein digestion. This proteolytic activity contributes to efficient dietary protein breakdown and nutrient absorption. Genetic variation in CTRB1 has been associated with susceptibility to pancreatic diseases and metabolic traits, reflecting its physiological relevance in exocrine pancreatic function and digestive system health.
CABT-BL4452 is suitable for use in ELISA (1:4,000–1:8,000), IHC (1:50–1:100), Western blot (WB) (1:1,000–1:4,000) applications.
CABT-BL4452 is supplied as a liquid formulation in 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. For long-term storage, keep at −20 °C. For short-term use, store at 2–8 °C. Avoid repeated freeze–thaw cycles to maintain antibody integrity and performance.
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