Anti-CREG1 monoclonal antibody (DMABT-H13505)

Mouse anti-Human CREG1 monoclonal antibody for WB, IHC, sELISA, ELISA Datasheet

Bring this labeled antibody directly to your bench!

Online Inquiry Add to basket

Specifications


Host Species
Mouse
Antibody Isotype
IgG1
Clone
2C8
Species Reactivity
Human
Immunogen
CREG1 (NP_003842,232a.a. ~ 220 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Conjugate
Unconjugated

Target


Alternative Names
CREG1; cellular repressor of E1A-stimulated genes 1; cellular repressor of E1A stimulated genes , CREG; protein CREG1; CREG
Entrez Gene ID
UniProt ID

Product Background


Gene summary
CREG1 (Cellular Repressor Of E1A Stimulated Genes 1) is a Protein Coding gene. Among its related pathways are Senescence and Autophagy. GO annotations related to this gene include oxidoreductase activity and transcription corepressor activity. An important paralog of this gene is CREG2. The adenovirus E1A protein both activates and represses gene expression to promote cellular proliferation and inhibit differentiation. The protein encoded by this gene antagonizes transcriptional activation and cellular transformation by E1A. This protein shares limited sequence similarity with E1A and binds both the general transcription factor TBP and the tumor suppressor pRb in vitro. This gene may contribute to the transcriptional control of cell growth and differentiation.
Antigen Description
May contribute to the transcriptional control of cell growth and differentiation. Antagonizes transcriptional activation and cellular transformation by the adenovirus E1A protein. The transcriptional control activity of cell growth requires interaction with IGF2R. Protein CREG1 is a protein that in humans is encoded by the CREG1 gene. 0The function about CREG1 antigen include FMN binding; oxidoreductase activity; transcription corepressor activity; transcription factor binding.
Pathway
Senescence and Autophagy, organism-specific biosystem.

Citations


Have you cited DMABT-H13505 in a publication? Let us know and earn a reward for your research.

References


Peng, F; Han, YL; et al. Overexpression of cellular repressor of E1A-stimulated genes inhibits TNF-alpha-induced apoptosis via NF-kappa B in mesenchymal stem cells. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 406:601-607(2011).
Peng, CF; Han, YL; et al. Overexpressing Cellular repressor of E1A-stimulated genes promote hypoxia-induced VEGF paracrine via HIF-1 alpha in mesenchymal stem cells. CARDIOLOGY 126:48-48(2013).

Custom Antibody Labeling


We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

Customer Reviews


Write a review, share your experiences with others and get rewarded !

Online Inquiry

Name
Phone *
E-mail Address *
Service & Products Interested *
Project Description
Verification Code * Please input "diagnostics" as verification code.

Online Inquiry

Order Info: Anti-CREG1 monoclonal antibody

Online Inquiry
  Interested in larger quantities ? request a quote!
  Protocol may be improved. Please feel free to contact us to obtain the latest version.!
  15% off your first purchase

Ordering Information

Payment methods we support:
Invoice / Purchase Order
Credit card

OUR PROMISE TO YOU Guaranteed product quality expert customer support

Inquiry Basket