General Notes
This product (Catalog No. CABT-BL1113) is a rabbit-derived polyclonal antibody raised against human COL13A1, targeting the amino acid region 41–90 of the protein. This antibody exhibits cross-reactivity with COL13A1 from mouse. It has been affinity purified by Protein A. This gene encodes the alpha chain of one of the nonfibrillar collagens. The function of this gene product is not known, however, it has been detected at low levels in all connective tissue-producing cells so it may serve a general function in connective tissues. Unlike most of the collagens, which are secreted into the extracellular matrix, collagen XIII contains a transmembrane domain and the protein has been localized to the plasma membrane. The transcripts for this gene undergo complex and extensive splicing involving at least eight exons. Like other collagens, collagen XIII is a trimer; it is not known whether this trimer is composed of one or more than one alpha chain isomer. A number of alternatively spliced transcript variants have been described, but the full length nature of some of them has not been determined.
CABT-BL1113 is suitable for use in Western blot (WB) (1:500–1:2,000) application.
CABT-BL1113 is supplied as a liquid formulation in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. For long-term storage, keep at −20 °C. For short-term use, store at 2–8 °C. Avoid repeated freeze–thaw cycles to maintain antibody integrity and performance.