General Notes
This product (Catalog No. CABT-BL1103) is a rabbit-derived IgG polyclonal antibody raised against human CNTN3, targeting the amino acid region 301–400 of the protein. This antibody exhibits cross-reactivity with CNTN3 from rat, mouse, chicken, dog, cow, horse, and rabbit. It has been affinity purified by Protein A. Contactin 3 (CNTN3), also known as plasmacytoma-associated neuronal glycoprotein (PANG) or brain-derived immunoglobulin superfamily member 1 (BIG-1), is a glycosylphosphatidylinositol (GPI)-anchored cell adhesion molecule encoded by the CNTN3 gene located on the short arm of human chromosome 3 at locus 3p12.3. As a member of the contactin subfamily within the immunoglobulin (Ig) superfamily of neural cell adhesion molecules (IgCAMs), it features a characteristic extracellular structure comprising six N-terminal Ig-like domains (Ig1–Ig6) arranged in a conserved "horseshoe" conformation for ligand binding, followed by four fibronectin type III (FNIII) domains, and lacks both transmembrane and intracellular domains, enabling it to exist in membrane-bound and soluble secreted forms.
CABT-BL1103 is suitable for use in IHC-P (1:100–1:500), IHC-F (1:100–1:500), IF (immunofluorescence) (1:100–1:500) applications.
CABT-BL1103 is supplied as a liquid formulation in 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. For long-term storage, keep at −20 °C. For short-term use, store at 2–8 °C. Avoid repeated freeze–thaw cycles to maintain antibody integrity and performance.
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