Product Overview
Protein length: Protein fragment
Amino Acid Sequence: The protein contains the Cytomegalovirus (CMV) gB immunodominant regions.
Biological activity: Immunoreactive with sera of CMV infected individuals.
Tag/Conjugate
Unconjugated
Alternative Names
CMV glycoprotein B; Glycoprotein B; HCMV; HHV5 glycoprotein B; UL55
Purity
> 95 % by SDS-PAGE. Sepharose derived purification.
Concentration
Batch dependent - please inquire should you have specific requirements.
Buffer
Constituents: 50% Glycerol, 25mM Tris HCl, 1mM EDTA, pH 7.2
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Introduction
Cytomegalovirus is a member of the herpes virus group, which includes herpes simplex virus types 1 and 2, varicella zoster virus (which causes chicken pox), and Epstein Barr virus (which causes infectious mononucleosis). These viruses share a characteristic ability to remain dormant within the body over a long period.
Antigen Description
Human cytomegalovirus (HCMV) glycoprotein B (gB) is an abundant virion envelope protein that has been shown to be essential for the infectivity of HCMV. HCMV gB is also one of the most immunogenic virus-encoded proteins, and a significant fraction of virus neutralizing antibodies are directed at gB.
Keywords
CMV glycoprotein B; Glycoprotein B; HCMV; HHV5 glycoprotein B; UL55
Citations
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