Product Overview
Blocking/Immunizing peptide for anti-CLIM1/PDLIM1 antibody
Tag/Conjugate
Unconjugated
Application Notes
For in vitro research use only. Not intended for any diagnostic or therapeutic purpose. Not for human or animal consumption.
Format
Lyophilized powder
Storage
Shipped at ambient temperature, store at -20°C.
Antigen Description
This gene encodes a member of the enigma protein family. The protein contains two protein interacting domains, a PDZ domain at the amino terminal end and one to three LIM domains at the carboxyl terminal. It is a cytoplasmic protein associated with the cytoskeleton. The protein may function as an adapter to bring other LIM-interacting proteins to the cytoskeleton. Pseudogenes associated with this gene are located on chromosomes 3, 14 and 17. [provided by RefSeq, Oct 2012]
Function
metal ion binding; transcription coactivator activity; zinc ion binding;
Synonyms
PDLIM1; PDZ and LIM domain 1; CLIM1, PDZ and LIM domain 1 (elfin); PDZ and LIM domain protein 1; carboxyl terminal LIM domain protein 1; CLP 36; CLP36; elfin; hCLIM1; enigma; LIM domain protein CLP-36; C-terminal LIM domain protein 1; carboxy terminal LIM domain protein 1; CLIM1; CLP-36;
Citations
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Marie, H; Billups, D; et al. The amino terminus of the glial glutamate transporter GLT-1 interacts with the LIM protein Ajuba. MOLECULAR AND CELLULAR NEUROSCIENCE 19:152-164(2002).
Foletta, VC; Moussi, N; et al. LIM kinase 1, a key regulator of actin dynamics, is widely expressed in embryonic and adult tissues. EXPERIMENTAL CELL RESEARCH 294:392-405(2004).