Fusion protein corresponding to a region derived from internal residues of human claudin 23
Conjugate
Unconjugated
Applications
Application Notes
WB: 1:200-1:1000 IHC: 1:25-1:100
General Notes
This product (Catalog No. CABT-BL1073) is a rabbit-derived IgG polyclonal antibody raised against human CLDN23. It has been affinity purified by protein A. This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. This gene is expressed in germinal center B-cells, placenta and stomach as well as in colon tumor. This gene is down-regulated in intestinal type gastric cancer. CABT-BL1073 is suitable for use in Western blot (WB) (1:200–1:1,000), IHC (1:25–1:100) applications. CABT-BL1073 is supplied as a liquid formulation in pH7.4 PBS, 0.05% sodium azide, 40% Glycerol. For long-term storage, keep at −20 °C. For short-term use, store at 2–8 °C. Avoid repeated freeze–thaw cycles to maintain antibody integrity and performance.
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