Human CHN2 blocking peptide (CDBP0789)

Synthetic Human CHN2 blocking peptide for Apuri, BL, ELISA Datasheet

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Product Overview
Blocking/Immunizing peptide for anti-CHN2 antibody
Target
CHN2
Nature
Synthetic
Species Reactivity
Human, Mouse, Cow, Dog
Tag/Conjugate
Unconjugated
Application Notes
For in vitro research use only. Not intended for any diagnostic or therapeutic purpose. Not for human or animal consumption.
Format
Lyophilized powder
Size
100 μg
Storage
Shipped at ambient temperature, store at -20°C.
UniProt ID
Antigen Description
This gene encodes a guanosine triphosphate (GTP)-metabolizing protein that contains a phorbol-ester/diacylglycerol (DAG)-type zinc finger, a Rho-GAP domain, and an SH2 domain. The encoded protein translocates from the cytosol to the Golgi apparatus membrane upon binding by diacylglycerol (DAG). Activity of this protein is important in cell proliferation and migration, and expression changes in this gene have been detected in cancers. A mutation in this gene has also been associated with schizophrenia in men. Alternative transcript splicing and the use of alternative promoters results in multiple transcript variants.
Function
GTPase activator activity; Rac GTPase activator activity; SH3/SH2 adaptor activity; metal ion binding;
Synonyms
CHN2; chimerin (chimaerin) 2; beta-chimaerin; ARHGAP3; beta chimerin; RhoGAP3; beta-chimerin; beta3-chimaerin; rho-GTPase-activating protein 3; BCH; CHN2-3; RHOGAP3; MGC138360;

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