The CHD family of proteins is characterized by the presence of chromo (chromatin organization modifier) domains and SNF2-related helicase/ATPase domains. CHD genes alter gene expression possibly by modification of chromatin structure thus altering access of the transcriptional apparatus to its chromosomal DNA template.
Function
ATP binding; ATP-dependent DNA helicase activity; DNA binding; helicase activity; hydrolase activity; methylated histone residue binding; nucleotide binding;
Synonyms
CHD1; chromodomain helicase DNA binding protein 1; chromodomain-helicase-DNA-binding protein 1; CHD-1; ATP-dependent helicase CHD1; DKFZp686E2337;
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