Product Overview
Blocking/Immunizing peptide for anti-CENTD3/ARAP3 antibody
Tag/Conjugate
Unconjugated
Application Notes
For in vitro research use only. Not intended for any diagnostic or therapeutic purpose. Not for human or animal consumption.
Format
Lyophilized powder
Storage
Shipped at ambient temperature, store at -20°C.
Antigen Description
This gene encodes a phosphoinositide binding protein containing ARF-GAP, RHO-GAP, RAS-associating, and pleckstrin homology domains. The ARF-GAP and RHO-GAP domains cooperate in mediating rearrangements in the cell cytoskeleton and cell shape. It is a specific PtdIns(3,4,5)P3/PtdIns(3,4)P2-stimulated Arf6-GAP protein. An alternatively spliced transcript has been found for this gene, but its biological validity has not been determined.
Function
ARF GTPase activator activity; NOT Rac GTPase activator activity; Rho GTPase activator activity; Rho GTPase activator activity; metal ion binding; phosphatidylinositol-3,4,5-trisphosphate binding; phosphatidylinositol-3,4-bisphosphate binding; zinc ion bi
Synonyms
ARAP3; ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3; centaurin, delta 3 , CENTD3; arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3; DRAG1; FLJ21065; cnt-d3; centaurin-delta-3; centaurin, delta 3; PtdIns(3,4,5)P3-binding protein; phosphoinositide binding protein; Arf and Rho GAP adapter protein 3; ARF-GAP, RHO-GAP, ankyrin repeat and plekstrin homology domains-containing protein 3; CENTD3;
Citations
Publication ()
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