Specificity: CENPC1 Antibody detects endogenous levels of total CENPC1.
Host: Rabbit
Application: WB, IHC
Species Reactivity: Human; Predicted: Pig, Horse, Sheep, Rabbit, Dog
Summary
Specifications
Antibody Isotype
IgG
Species Reactivity
Human
Immunogen
A synthesized peptide derived from human CENPC1, corresponding to a region within C-terminal amino acids.
Conjugate
Unconjugated
Applications
Application Notes
WB 1:1000-3000 IHC 1:50-1:200
General Notes
This product (Catalog No. CABT-BL1036) is a rabbit-derived polyclonal antibody raised against human CENPC1. It has been affinity purified by Protein A. Component of the CENPA-NAC (nucleosome-associated) complex, a complex that plays a central role in assembly of kinetochore proteins, mitotic progression and chromosome segregation. The CENPA-NAC complex recruits the CENPA-CAD (nucleosome distal) complex and may be involved in incorporation of newly synthesized CENPA into centromeres. CENPC recruits DNA methylation and DNMT3B to both centromeric and pericentromeric satellite repeats and regulates the histone code in these regions. CABT-BL1036 is suitable for use in WB 1 (1000-3000), IHC 1 (50-1:200) applications. CABT-BL1036 is supplied as a liquid formulation in Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. For long-term storage, keep at −20 °C. For short-term use, store at 2–8 °C. Avoid repeated freeze–thaw cycles to maintain antibody integrity and performance.
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