Rabbit Anti-Human Cdc42EP5 (N-terminal) Polyclonal antibody

Antibody Isotype

IgG

Species Reactivity

Human; Mouse

Immunogen

Synthesized peptide derived from the N-terminal region of human Cdc42EP5.

Conjugate

Application Notes

WB: 1:500-1:2000
IHC: 1:100-1:300
ELISA: 1:40000

General Notes

This product (Catalog No. CABT-BL1019) is a rabbit-derived polyclonal antibody raised against human CDC42EP5. This antibody exhibits cross-reactivity with CDC42EP5 from mouse. It has been affinity purified by Protein A. Cell division control protein 42 (CDC42), a small Rho GTPase, regulates the formation of F-actin-containing structures through its interaction with the downstream effector proteins. The protein encoded by this gene is a member of the Borg (binder of Rho GTPases) family of CDC42 effector proteins. Borg family proteins contain a CRIB (Cdc42/Rac interactive-binding) domain. They bind to CDC42 and regulate its function negatively. The encoded protein may inhibit c-Jun N-terminal kinase (JNK) independently of CDC42 binding. The protein may also play a role in septin organization and inducing pseudopodia formation in fibroblasts.
CABT-BL1019 is suitable for use in Western blot (WB) (1:500–1:2,000), IHC (1:100–1:300), ELISA (1:40000) applications.
CABT-BL1019 is supplied as a liquid formulation in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. For long-term storage, keep at −20 °C. For short-term use, store at 2–8 °C. Avoid repeated freeze–thaw cycles to maintain antibody integrity and performance.

Alternative Names

CDC42EP5; BORG3; CEP5; Cdc42 effector protein 5; Binder of Rho GTPases 3

Entrez Gene ID

UniProt ID