Rabbit Anti-Human CCDC157 (a.a. 223-491) Polyclonal antibody

Antibody Isotype

IgG

Species Reactivity

Human; Mouse

Immunogen

Recombinant human CCDC157 protein; Source: E. coli derived, PGEX-4T; Tag: GST; Domain: 223-491 aa of BC092419

Conjugate

Application Notes

WB: 1:500-1:1000

General Notes

This product (Catalog No. CABT-BL857) is a rabbit-derived polyclonal antibody raised against human CCDC157, targeting the amino acid region 223–491 of the protein. This antibody exhibits cross-reactivity with Human CCDC157 from mouse. It has been affinity purified by Protein A. CCDC157 is a member of the coiled-coil domain-containing (CCDC) family proteins, wich have a conserved coiled-coil motif that is responsible for molecular recognition and protein refolding. CCDC157 is highly expressed in the testes from Drosophila to mammals. Bioinformatics database analysis suggests that CCDC157 expression is significantly decreased in NOA patients (PMID: 30741974). An in vitro study has reported that CCDC157 is localized on Golgi membranes along the secretory pathway and interacts with resident proteins of ER-Golgi membranes (PMID: 31488582).
CABT-BL857 is suitable for use in Western blot (WB) (1:500–1:1,000) application.
CABT-BL857 is supplied as a liquid formulation in PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. For long-term storage, keep at −20 °C. For short-term use, store at 2–8 °C. Avoid repeated freeze–thaw cycles to maintain antibody integrity and performance.

Alternative Names

KIAA1656; Coiled-coil domain-containing protein 157

Entrez Gene ID

UniProt ID