Product Overview
Blocking/Immunizing peptide for anti-CBLC antibody
Tag/Conjugate
Unconjugated
Application Notes
For in vitro research use only. Not intended for any diagnostic or therapeutic purpose. Not for human or animal consumption.
Format
Lyophilized powder
Storage
Shipped at ambient temperature, store at -20°C.
Antigen Description
This gene encodes a member of the Cbl family of E3 ubiquitin ligases. Cbl proteins play important roles in cell signaling through the ubiquitination and subsequent downregulation of tyrosine kinases. Expression of this gene may be restricted to epithelial cells, and alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Function
SH3 domain binding; calcium ion binding; epidermal growth factor receptor binding; phosphotyrosine binding; signal transducer activity; ubiquitin-protein ligase activity; zinc ion binding;
Synonyms
CBLC; Cbl proto-oncogene, E3 ubiquitin protein ligase C; Cas Br M (murine) ecotropic retroviral transforming sequence c , Cas Br M (murine) ectropic retroviral transforming sequence c; signal transduction protein CBL-C; CBL 3; CBL SL; RNF57; RING finger protein 57; SH3-binding protein CBL-3; SH3-binding protein CBL-C; Cas-Br-M (murine) ectropic retroviral transforming sequence c; Cas-Br-M (murine) ecotropic retroviral transforming sequence c; CBL-3; CBL-SL;
Citations
Publication ()
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