1.0 mg/ml (see Certificate of Analysis for actual concentration)
Buffer
10 mM sodium phosphate, 145 mM NaCl, pH 7.3
Preservative
None
Storage
2-8°C short term, -20°C long term
Introduction
This gene encodes a component of the complement cascade. The encoded protein is part of the membrane attack complex that can be incorporated into the cell membrane and cause cell lysis. Mutations in this gene are associated with complement component-6 deficiency. Transcript variants encoding the same protein have been described.[provided by RefSeq, Nov 2012]
Antigen Description
Native human C6 is a naturally glycosylated (11%) protein composed of a single polypeptide chain of 105,000 Da. C6 is essential for formation of the membrane attack complex (MAC) and is activated non-proteolytically by binding to recently-formed C5b at th
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